3rd U-PGx Personalized Medicine Day, Toulouse, France

Clinical application of pharmacogenomics knowledge will result in less ‘trial and error’ prescribing and more efficacious, safer and cost-effective drug therapy. However, despite the major advances in pharmacogenomics and several commercially available pharmacogenomics tests, its application in routine patient care remains very limited. The U-PGx consortium will address major challenges and obstacles for implementation of pharmacogenomics testing in patient care, taking into account the diversity of healthcare systems and citizens across Europe. Specifically, U-PGx will investigate if the emerging approach of pre-emptive genotyping of an entire panel of important pharmacogenomics markers is cost-effective and results in a better outcome for patients. With the pre-emptive pharmacogenomics testing approach data on multiple important pharmacogenes are collected prospectively and embedded into the patients’ electronic record. Typically, it alerts prescribers and pharmacists through electronic clinical decision support systems when a drug is ordered or dispensed for a patient with an at-risk genotype. The new model of personalised medicine through pre-emptive pharmacogenomics testing will be conducted at a large scale in seven existing European health care environments in the Netherlands, Spain, UK, Italy, Austria, Greece, and Slovenia.

Invited speakers

Organizing Committee

Emmanuelle Rial-Sebbag; Director of Research, University of Toulouse, Toulouse, France

George P. Patrinos; Associate Professor, University of Patras Department of Pharmacy, Patras, Greece

Keynote Speaker

Anne Cambon-Thomsen (Toulouse, FR)

Plenary Speakers

James Buchanan (Oxford, UK)

Ingolf Cascorbi (Kiel, DE)

Erica Cecchin (Aviano, IT)

Heidi C. Howard (Uppsala, SE)

Sandrine de Montgolfier (Toulouse, FR)

George P. Patrinos (Patras, GR)

Emmanuelle Rial-Sebbag (Toulouse, FR)

Fabienne Thomas-Jean (Toulouse, FR)

{tab Scientific Program}

The official language of the Conference is FRENCH – Selected lectures will be delivered in English

Scientific Program

8:30 – 9:30      Registration

9:30 – 9:45      Welcome addresses

Emmanuelle Rial-Sebbag; Director of Research, University of Toulouse, Toulouse, France

George P. Patrinos; Associate Professor, University of Patras, Department of Pharmacy, Patras, Greece

9:45 – 10:15   Pharmacogenomics to increase anti-cancer drugs safety: From research to clinical implementation (in English)

Erika Cecchin; Senior Scientist, Cancer Research Organization, Aviano, Italy

10:15 – 11:00 Keynote lecture: Ethics of Biotechnologies

Anne Cambon-Thomsen; Professor; University of Toulouse, Toulouse, France

11:00 – 11:30 Pharmacogenetics-based personalized therapy: Levels of evidence and recommendations from the French Network of Pharmacogenetics (RNPGx)

Fabienne Thomas-Jean; MCU-PH; Toulouse, France

11:30 – 12:00 Genetic and Epigenetic mechanisms of TKI resistance (in English)

Ingolf Cascorbi; Professor, University of Kiel, Kiel, Germany

12:00 – 13:30  Lunch Break (Free-of-charge; lunch coupons will be available from the secretariat)

13:30 – 14:00 Economic evaluation in cancer pharmacogenomics (in English)

James Buchanan; Assistant Professor; University of Oxford, Nuffield Department of Population Health, Oxford, UK

14:00 – 14:30 Legal issues in Pharmacogenomics

Emmanuelle Rial-Sebbag; Director of Research, University of Toulouse, Toulouse, France

14:30 – 15:00 Cancer, pharmacogenomics and ethics: Lessons from practices

Sandrine de Montgolfier; Faculty, University of Toulouse, Toulouse, France

15:00 – 15:30 Coffee/Tea break

15:30 – 16:00 Ethics and Pharmacogenomics

Heidi Howard; Staff Scientist, Center for Research Ethics and Bioethics, Uppsala, Sweden

16:00 – 16:30 Public Health Pharmacogenomics (in English)

George P. Patrinos; Associate Professor, University of Patras, Department of Pharmacy, Patras, Greece

16:30 – 16:40 Closing remarks

Emmanuelle Rial-Sebbag; Director of Research, University of Toulouse, Toulouse, France

Presentations

Here you can find available presentations from the event.