Pharmacogenomics in Europe

 It is known that for most common diseases there are a number of medications from which to select therapy and usually a large individual variability in response to any given drug, ranging from no response to disease resolution. There is also the issue of under-representation of many countries in the development of medicines. Variation in DNA does help explain some of the differences in a person’s response to a medication, but the cost of individual genetic testing will be prohibitive for many countries for the foreseeable future.

In 2010, the Golden Helix Foundation has initiated the Euro-PGx project and is coordinating the recruitment of cases from various European developing countries. The coordinator of the Euro-PGx project is Prof. George P. Patrinos and so far, the following countries have joined this initiative in Europe (in alphabetical order):

Albania

Coordinator: Markus Paulmichl; Paracelsus Medical University, Salzburg

Austria

Coordinator: Markus Paulmichl; Paracelsus Medical University, Salzburg

Bosnia and Herzegovina

Coordinator: Sabina Semiz; University of Sarajevo, Faculty of Pharmacy, Sarajevo, Bosnia and Herzegovina

Bulgaria

Coordinator: Radka Kaneva; Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, Bulgaria

Croatia

Coordinator: Jadranka Setric, Nada Bozina; University Hospital Centre, Zagreb, Croatia

Cyprus

Coordinator: Constantinos Deltas; University of Cyprus, Nicosia

Czech Republic

Coordinator: Milan Macek; Charles University, Prague

Georgia

Coordinator: Alexander Lezhava, Javakhishvili; Tbilisi State University and Kipshidze University Hospital, Teimuraz Lezhava (Tbilisi State University), Nicholas Kipshidze (Kipshidze University Hospital), Tbilisi, Georgia

Germany

Coordinator: Ingolf Cascorbi; University Hospital Schleswig-Holstein, University of Kiel, Kiel

Greece

Coordinator: George P. Patrinos; University of Patras, Patras

Hungary

Coordinator: Istvan Balogh; University of Debrecen, Hungary

Italy

Coordinator: Maria del Zompo, University of Cagliari; Giuseppe Saglio, University of Torino; Giuseppe Novelli, University of Rome

Kosovo

Coordinator: Markus Paulmichl; Paracelsus Medical University, Salzburg

Lithuania

Coordinator: Vaidutis Kucinskas; Vilnius University Hospital, Vilnius, Lithuania

Malta

Coordinators: Anthony Fenech, Godfrey Grech, Joseph Borg; University of Malta

The Netherlands

Coordinators: Ron van Schaik, Ron Mathijssen; Erasmus MC, Rotterdam

Poland

Coordinator: Beata Burzynska; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw

Portugal

Coordinator: Rui Medeiros; Instituto Português de Oncologia, Porto

Romania

Coordinator: Maria Puiu, University of Medicine and Pharmacy "Victor Babes" Timisoara

Russia

Coordinator: Elza Khusnutdinova; Genomics Department, Institute of Biochemistry and Genetics, Ufa Sci Center of RAS, Ufa, Russia

Serbia

Coordinator: Sonja Pavlovic; Institute of Molecular Genetics and Genetic Engineering, Belgrade

Slovakia

Coordinator: Ludevit Kadasi; Comenius University, Faculty of Natural Sciences, Bratislava, Slovakia

Slovenia

Coordinator: Vita Dolzan; University of Ljubljana School of Medicine, Ljubljana

Spain

Coordinator: Miquel Taron; on behalf of the Spanish Society of Pharmacogenetics and Pharmacogenomics (SEFF)

Turkey

Coordinator: Nazli Basak; Boğaziçi University, Istanbul

Ukraine

Coordinator: Halyna Makukh; Institute of Hereditary Pathology, Lviv, Ukraine

 

Related publications

  • Mitropoulos K, Johnson L, Vozikis A, Patrinos GP. 2011. Relevance of pharmacogenomics for developing countries in Europe. Drug Metabol Drug Interact, 26(4):143-146.

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